Avocadyne
Avocadyne is an orally active mitochondrial fatty acid oxidation (FAO) inhibitor. Avocadyne induces leukemia cell death and reverses diet-induced obesity. Avocadyne inhibits fatty acid oxidation activity in leukemia cells. Avocadyne can be used in studies related to leukemia and obesity.
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- CAS No.: 129099-93-0
- Formule: C17H32O3
- Masse moléculaire:284.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A498 | IC50 |
4.1 μg/mL
Compound: 3
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Cytotoxicity against human A498 cells by MTT assay
Cytotoxicity against human A498 cells by MTT assay
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[PMID: 9644064] |
| A549 | IC50 |
4.8 μg/mL
Compound: 3
|
Cytotoxicity against human A549 cells by MTT assay
Cytotoxicity against human A549 cells by MTT assay
|
[PMID: 9644064] |
| HT-29 | IC50 |
8.9 μg/mL
Compound: 3
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Cytotoxicity against human HT-29 cells by MTT assay
Cytotoxicity against human HT-29 cells by MTT assay
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[PMID: 9644064] |
| MCF7 | IC50 |
6.5 μg/mL
Compound: 3
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Cytotoxicity against human MCF7 cells by MTT assay
Cytotoxicity against human MCF7 cells by MTT assay
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[PMID: 9644064] |
| MIA PaCa-2 | IC50 |
>10 μg/mL
Compound: 3
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Cytotoxicity against human MIAPaCa2 cells by MTT assay
Cytotoxicity against human MIAPaCa2 cells by MTT assay
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[PMID: 9644064] |
| PC-3 | IC50 |
0.61 ng/mL
Compound: 3
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Cytotoxicity against human PC3 cells by MTT assay
Cytotoxicity against human PC3 cells by MTT assay
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[PMID: 9644064] |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 129099-93-0
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Masse moléculaire 284.44
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Formule C17H32O3
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SMILES
C(CCCCCCCCCCC#C)[C@H](C[C@H](CO)O)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ahmed N, et al.. Bioaccessibility of avocado polyhydroxylated fatty alcohols. Food chemistry. 2025 Jan 15;463(Pt 1):140811. [Content Brief]
[2]. Tcheng M, et al.. Avocado-derived avocadyne is a potent inhibitor of fatty acid oxidation. Journal of food biochemistry. 2022 Mar;46(3):e13895. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Avocadyne Related Classifications
HY-W746606 Related Classifications
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