BC‐AZIDE
BC‐AZIDE (CLIP-AZIDE) is a CLIP-tag substrate that forms a covalent irreversible linkage with CLIP-tag proteins. When paired with conjugated fluorophores, BC‐AZIDE enables specific labeling of CLIP-tagged proteins in live and fixed cells. BC‐AZIDE can be used for research related to bioorthogonal click chemistry and intracellular orthogonal labeling.
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- CAS No.: 2432950-51-9
- Formule: C18H23N7O4
- Masse moléculaire:401.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Help & FAQs
Activité biologique
Description
In Vitro
BC-AZIDE (30 min) mediates SPAAC labeling of the nuclear envelope and actin fibers by DBCO-PEG4-5/6-TAMRA in live HeLa cells, enables SPAAC/IEDDA dual labeling of SNAP-/CLIP-tag fusion proteins in live cells with no obvious cross-reactivity, and also accomplishes two-color SPAAC/IEDDA labeling of CLIP-tag targets in fixed-permeabilized HeLa cells[2][3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2432950-51-9
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Masse moléculaire 401.42
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Formule C18H23N7O4
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SMILES
[N-]=[N+]=NCCOCCOCC(NCC1=CC=C(C=C1)COC2=NC(N)=CC=N2)=O
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Synonyms
CLIP-AZIDE
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BC‐AZIDE Related Classifications
HY-D2955 Related Classifications
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