2432950-51-9
Chemical Structure
BC‐AZIDE
Synonym(s): CLIP-AZIDE
- CAS No.: 2432950-51-9
- Formula:C18H23N7O4
- Molecular Weight:401.42
InChIKey: MSCQEZZWVONJFU-UHFFFAOYSA-N
SMILES: [N-]=[N+]=NCCOCCOCC(NCC1=CC=C(C=C1)COC2=NC(N)=CC=N2)=O
Biological Activity: BC‐AZIDE (CLIP-AZIDE) is a CLIP-tag substrate that forms a covalent irreversible linkage with CLIP-tag proteins. When paired with conjugated fluorophores, BC‐AZIDE enables specific labeling of CLIP-tagged proteins in live and fixed cells. BC‐AZIDE can be used for research related to bioorthogonal click chemistry and intracellular orthogonal labeling[1][2][3].
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BC‐AZIDE | BC‐AZIDE (CLIP-AZIDE) is a CLIP-tag substrate that forms a covalent irreversible linkage with CLIP-tag proteins. When paired with conjugated fluorophores, BC‐AZIDE enables specific labeling of CLIP-tagged proteins in live and fixed cells. BC‐AZIDE can be used for research related to bioorthogonal click chemistry and intracellular orthogonal labeling. | |||||||||||||||||||||
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References
- [1]. Gayathri V, et al. Functionalization of Bacterial Cellulose and Related Surfaces Using a Facile Coupling Reaction by Thermoresponsive Catalyst. ACS biomaterials science & engineering. 2023 Feb 13;9(2):625-641. [Content Brief]
- [2]. Krishnamurthy M, et al. Improved Hydrophobicity of a Bacterial Cellulose Surface: Click Chemistry in Action. ACS biomaterials science & engineering. 2020 Feb 10;6(2):879-888. [Content Brief]
- [3]. Macias-Contreras M, et al. SNAP/CLIP-Tags and Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC)/Inverse Electron Demand Diels-Alder (IEDDA) for Intracellular Orthogonal/Bioorthogonal Labeling. Bioconjugate chemistry. 2020 May 20;31(5):1370-1381. [Content Brief]