CCR-11
CCR-11 is an antibacterial agent. CCR-11 can inhibit the proliferation of B. subtilis cells with an IC50 value of 1.2 μM. CCR-11 inhibits HeLa cell proliferation with an IC50 value of 18.1 μM. CCR-11 inhibits bacterial cytokinesis by inhibiting FtsZ assembly. CCR-11 can be used for the research of FtsZ-targeted antibacterial agents.
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- CAS No.: 1287652-03-2
- Formule: C15H8F3NO2S2
- Masse moléculaire:355.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
IC50: 1.2 μM (B. subtilis); 18.1 μM (HeLa cell) [1].
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
18.1 μM
Compound: 14, CCR-11
|
Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
|
[PMID: 25791674] |
Chemical Information
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CAS No. 1287652-03-2
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Masse moléculaire 355.35
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Formule C15H8F3NO2S2
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SMILES
O=C1NC(S/C1=C/C2=CC=C(C3=CC=CC(C(F)(F)F)=C3)O2)=S
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)