(E/Z)-CCR-11
Based on 1 Customer Validation
(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 301687-87-6
- Formula: C15H8F3NO2S2
- Molecular Weight:355.35
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 301687-87-6
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Appearance Solid
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Molecular Weight 355.35
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Formula C15H8F3NO2S2
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Color Yellow to brown
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SMILES
O=C1NC(S/C1=C\C2=CC=C(C3=CC(C(F)(F)F)=CC=C3)O2)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (281.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8141 mL | 14.0706 mL | 28.1413 mL | 70.3532 mL |
| 5 mM | 0.5628 mL | 2.8141 mL | 5.6283 mL | 14.0706 mL | |
| 10 mM | 0.2814 mL | 1.4071 mL | 2.8141 mL | 7.0353 mL | |
| 15 mM | 0.1876 mL | 0.9380 mL | 1.8761 mL | 4.6902 mL | |
| 20 mM | 0.1407 mL | 0.7035 mL | 1.4071 mL | 3.5177 mL | |
| 25 mM | 0.1126 mL | 0.5628 mL | 1.1257 mL | 2.8141 mL | |
| 30 mM | 0.0938 mL | 0.4690 mL | 0.9380 mL | 2.3451 mL | |
| 40 mM | 0.0704 mL | 0.3518 mL | 0.7035 mL | 1.7588 mL | |
| 50 mM | 0.0563 mL | 0.2814 mL | 0.5628 mL | 1.4071 mL | |
| 60 mM | 0.0469 mL | 0.2345 mL | 0.4690 mL | 1.1726 mL | |
| 80 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8794 mL | |
| 100 mM | 0.0281 mL | 0.1407 mL | 0.2814 mL | 0.7035 mL |