DM-4103
DM-4103 is a major metabolite of Tolvaptan (HY-17000) that is metabolized primarily by the CYP3A4 enzyme in the liver. DM-4103 inhibits the ability of human liver transporters NTCP, BSEP, MRP2, MRP3, MRP4 (IC50 values are 16.3, 4.15, 51.0, 44.6, 4.26 μM, respectively) and bile acid transport in SCHH cells. DM-4103 can be used in the study of autosomal dominant polycystic kidney disease (ADPKD).
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- CAS No.: 1346599-56-1
- Formule: C26H23ClN2O5
- Masse moléculaire:478.92
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Chemical Information
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CAS No. 1346599-56-1
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Masse moléculaire 478.92
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Formule C26H23ClN2O5
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SMILES
CC1=CC=CC=C1C(NC2=CC(C)=C(C(NC3=C(C(CCC(O)=O)=O)C=C(Cl)C=C3)=O)C=C2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DM-4103 Related Classifications
HY-W702907 Related Classifications
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