FMS586 free base
FMS586 free base is a selective neuropeptide Y Y5 receptor antagonist with oral activity. FMS586 can completely block the significant increase in adrenocorticotropic hormone (ACTH) and cortisol caused by the Y(5) selective agonist hPP. FMS586 also reversed the significant upregulation of adrenocorticotropic hormone (CRF) and antidiuretic hormone (AVP) mRNA expression induced by central injection of hPP. FMS586 provides the first evidence that selective stimulation of Y(5) receptors triggers activation of the HPA axis.
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- CAS No.: 302556-51-0
- Formule: C24H30N4O
- Masse moléculaire:390.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 302556-51-0
-
Masse moléculaire 390.52
-
Formule C24H30N4O
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SMILES
O=C(N(CCC1=CC=NC=C1)C)NC2=CC3=C(N(C4=C3CCCC4)C(C)C)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FMS586 free base Related Classifications
HY-118768 Related Classifications
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