Forasartan
Forasartan is an nonpeptide angiotensin AT1 receptor antagonist with an IC50 of 2.9 nM. Forasartan is also an anti-hypertension agent. Forasartan significantly inhibits preganglionic stimulation in a dose-dependent manner in vivo. Forasartan can inhibit the heart rate increase induced by angiotensin II.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 145216-43-9
- Formule: C23H28N8
- Masse moléculaire:416.52
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Angiotensin Receptor
More
Activité biologique
Chemical Information
-
CAS No. 145216-43-9
-
Masse moléculaire 416.52
-
Formule C23H28N8
-
SMILES
CCCCC1=NC(CCCC)=NN1CC2=CN=C(C3=CC=CC=C3C4=NNN=N4)C=C2
-
Synonyms
SC-52458
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Tokunaga, R., et al., (2001). Possible involvement of calcium-calmodulin pathways in the positive chronotropic response to angiotensin II on the canine cardiac sympathetic ganglia. Japanese journal of pharmacology, 86(4), 381-389. [Content Brief]
[2]. Gul, F., Parvaiz, N., & Azam, S. S. (2023). Deciphering the relational dynamics of AF-2 domain of PAN PPAR through drug repurposing and comparative simulations. PloS one, 18(3), e0283743. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)