FPPS-IN-2
FPPS-IN-2 (compound 4a) is a potent and orally active HFPPS inhibitor with an IC50 value of 1.108 µM. FPPS-IN-2 has the potential for the research of osteoporosis.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C24H26O6
- Masse moléculaire:410.46
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 1.108 µM (HFPPS)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:200-250 g, Female Wistar rats[1]
-
Dosage:0.1, 1, 10 mg/kg
-
Administration:P.o.; daily for 8 weeks
-
Result:Increased the osteocalcin level only with the 1, and 10 mg/kg doses, reduced urinary calcium.
Chemical Information
-
Masse moléculaire 410.46
-
Formule C24H26O6
-
SMILES
COC1=CC(/C=C/C(C)=O)=CC=C1OCCOC2=CC=C(/C=C/C(C)=O)C=C2OC
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)