Kcnj2 - potassium inwardly-rectifying channel, subfamily J, member 2 Gene

Also Known as IRK1; Kcnf1; Kir2.1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16518

Summary

Enables identical protein binding activity. Acts upstream of or within cardiac muscle cell action potential and magnesium ion transport. Predicted to be located in several cellular components, including T-tubule; endoplasmic reticulum; and intercalated disc. Predicted to be intrinsic component of membrane. Predicted to be part of voltage-gated Potassium Channel complex. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in Andersen-Tawil syndrome; familial atrial fibrillation; familial periodic paralysis; and short QT syndrome. Orthologous to human KCNJ2 (potassium inwardly rectifying channel subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj2 Products (2)

mRNA Protein Name
NM_008425.4 NP_032451.1 inward rectifier potassium channel 2
NM_008425.4 NP_032451.1 inward rectifier potassium channel 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16834334 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11287423 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within cardiac muscle cell action potential IMP
IMP: Inferred from mutant phenotype
15581370 MGI
acts upstream of or within magnesium ion transport IDA
IDA: Inferred from direct assay
8189383 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

inward rectifier potassium channel 2

  • IRK-1

  • inward rectifier K(+) channel Kir2.1

  • potassium channel, inwardly rectifying subfamily J member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS07145 KCNJ2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20045 Kcnj2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26548 Kcnj2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnj2 NCBI NCBI:3759