KI 1769
KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease.
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- CAS No.: 133300-00-2
- Formule: C15H14N4
- Masse moléculaire:250.30
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vivo
KI 1769 (0.3 mg/kg, i.v.) prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 133300-00-2
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Masse moléculaire 250.30
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Formule C15H14N4
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SMILES
N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11(6):561-6. [Content Brief]
[2]. Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80(2):143-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KI 1769 Related Classifications
HY-105501 Related Classifications
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