133300-00-2
133300-00-2
Chemical Structure
KI 1769
- CAS No.: 133300-00-2
- Formula:C15H14N4
- Molecular Weight:250.30
IUPAC Name: (E)-N-cyano-N'-phenethylnicotinimidamide
InChIKey: SUPZSNPDPSPMTK-UHFFFAOYSA-N
SMILES: N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2
Biological Activity: KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease[1][2].
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KI 1769 | KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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References
- [1]. Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11(6):561-6. [Content Brief]
- [2]. Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80(2):143-53. [Content Brief]
Keywords
