KI 1769
KI 1769 is a potassium channel opener. KI 1769 can exhibit vasodilating effect. KI 1769 prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen. KI 1769 can be used for the research of cardiovascular disease.
For research use only. We do not sell to patients.
- CAS No.: 133300-00-2
- Formula: C15H14N4
- Molecular Weight:250.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
KI 1769 (0.3 mg/kg, i.v.) prolongs the micturition interval and reduces the resistance to fluid infusion through the urethral lumen in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 133300-00-2
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Molecular Weight 250.30
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Formula C15H14N4
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SMILES
N#CN/C(C1=CC=CN=C1)=N/CCC2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Izumi H, et al. In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives. Fundam Clin Pharmacol. 1997;11(6):561-6. [Content Brief]
[2]. Kontani H, et al. Effect of K+ channel openers, KRN2391 and Ki1769, and nitroglycerin on the urinary tract of rats in vivo. Jpn J Pharmacol. 1999 Jun;80(2):143-53. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)