Misakimycin
Misakimycin is a naphthoquinone compound. Misakimycin exhibits cytotoxicity against human melanoma, breast cancer and ovarian cancer cells. Misakimycin can be found in strains of the genus Pyrenochaetopsis (strain MSX63693). Misakimycin can be used in research related to melanoma, breast cancer and ovarian cancer.
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- CAS No.: 91776-49-7
- Formule: C13H12O5
- Masse moléculaire:248.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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- Pureté et documentation
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDA-MB-231 | IC50 |
15 μM
Compound: 6
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Cytotoxicity against human MDA-MB-231 cells after 72 hrs by Cell Titer-Blue cell viability assay
Cytotoxicity against human MDA-MB-231 cells after 72 hrs by Cell Titer-Blue cell viability assay
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[PMID: 33006889] |
| MDA-MB-435 | IC50 |
3.2 μM
Compound: 6
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Cytotoxicity against human MDA-MB-435 cells after 72 hrs by Cell Titer-Blue cell viability assay
Cytotoxicity against human MDA-MB-435 cells after 72 hrs by Cell Titer-Blue cell viability assay
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[PMID: 33006889] |
| OVCAR-3 | IC50 |
9.6 μM
Compound: 6
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Cytotoxicity against human OVCAR-3 cells after 72 hrs by Cell Titer-Blue cell viability assay
Cytotoxicity against human OVCAR-3 cells after 72 hrs by Cell Titer-Blue cell viability assay
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[PMID: 33006889] |
In Vitro
Misakimycin (72 h) inhibits the growth of human melanoma MDA-MB-435 cells, human breast cancer MDA-MB-231 cells, and human ovarian cancer OVCAR3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MDA-MB-435, MDA-MB-231, OVCAR3
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Concentration:/
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Incubation Time:72 h
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Result:Had an IC50 of 3.2 μM for MDA-MB-435 cells, 15 μM for MDA-MB-231 cells and 9.6 μM for OVCAR3 cells.
Chemical Information
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CAS No. 91776-49-7
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Masse moléculaire 248.23
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Formule C13H12O5
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SMILES
O=C1C(OC)=CC(C2=C1C=C(OC)C(C)=C2O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Misakimycin Related Classifications
HY-130451 Related Classifications
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