Nrf2 activator-9
Nrf2 activator-9 (compound D-36) is an Nrf2 activator that inhibits oxidized low-density lipoprotein (oxLDL) and high glucose (HG)-induced apoptosis in HUVEC cells. Nrf2 activator-9 inhibits oxLDL and HG-induced vascular endothelial cell (VEC) injury and can effectively prevent and treat atherosclerosis.
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- Formule: C26H27N5O4
- Masse moléculaire:473.52
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Description
In Vitro
Nrf2 activator-9 (compound D-36) (5 μM, 10 μM; 6 h) reverses 50 μg/mL oxLDL-induced HUVEC apoptosis[1].
Nrf2 activator-9 (5 μM, 10 μM; 6 h, 24 h) promotes the nuclear translocation of Nrf2, activates the antioxidant pathway of Nrf2, and forms a protective effect on HUVEC[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 473.52
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Formule C26H27N5O4
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SMILES
OC1=CC(/C=C/C(N2CCN(CC2)CC3=NOC(CC4=CNC5=CC=CC=C54)=N3)=O)=CC=C1OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nrf2 activator-9 Related Classifications
HY-156081 Related Classifications
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