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Cat. No.: HY-N10285

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Phaeosphaone D

Phaeosphaone D is a thiodiketopiperazine alkaloid compound isolated from Phaeosphaeria fuckelii, an endophytic fungus. Phaeosphaone D displays mushroom tyrosinase inhibitory activity with an IC₅₀ value of 33.2 μM.

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CAS No.: 2640137-78-4
Formule: C₂₀H₂₇N₃O₃S₂
Masse moléculaire:421.58

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Phaeosphaone D Chemical Structure

CAS No.: 2640137-78-4

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Activité biologique

Description

Phaeosphaone D is a thiodiketopiperazine alkaloid compound isolated from Phaeosphaeria fuckelii, an endophytic fungus. Phaeosphaone D displays mushroom tyrosinase inhibitory activity with an IC₅₀ value of 33.2 μM^[1].

Chemical Information

CAS No. 2640137-78-4
Masse moléculaire 421.58
Formule C₂₀H₂₇N₃O₃S₂
SMILES

CS[C@H](C1=CNC2=CC=CC=C12)[C@]3(C(N([C@@](SC)(C(N3)=O)C(C)C)C)=O)OC
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
- Microorganisms
Phaeosphaeria fuckelii
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhai YJ, et al. Phaeosphaones: Tyrosinase Inhibitory Thiodiketopiperazines from an Endophytic Phaeosphaeria fuckelii. J Nat Prod. 2020;83(5):1592-1597. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
Chemical Information
Protocole
Pureté et documentation
Références