Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

  • Blood Adv. 2023 May 9;7(9):1692-1696. doi: 10.1182/bloodadvances.2022008466.
Justin S Trory  1 ,  Attila Munkacsi  1 ,  Kamila M Śledź  1 ,  Jordan Vautrinot  1 ,  Lucy J Goudswaard  1  2 ,  Molly L Jackson  1 ,  Kate J Heesom  3 ,  Samantha F Moore  1 ,  Alastair W Poole  1 ,  Behnam Nabet  4 ,  Varinder K Aggarwal  5 ,  Ingeborg Hers  1
Affiliations
  • 1. School of Physiology, Pharmacology and Neuroscience, University of Bristol, University Walk, Biomedical Sciences Building, Bristol BS8 1TD, United Kingdom.
  • 2. Bristol Medical School, Population Health Sciences, University of Bristol, Oakfield House, Bristol, United Kingdom.
  • 3. Faculty of Life Sciences, Proteomics Facility, University of Bristol, University Walk, Biomedical Sciences Building, Bristol, United Kingdom.
  • 4. Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA.
  • 5. School of Chemistry, University of Bristol, Cantock's Close, Bristol, United Kingdom.
PMID: 36342848 DOI: 10.1182/bloodadvances.2022008466
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