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Ruxoprubart

(Synonyms: NM8074)
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Ruxoprubart (NM8074) is an inhibitor of complement factor B (Bb subunit). Ruxoprubart selectively binds to active Bb to inhibit the alternative complement pathway without affecting the classical complement pathway. By blocking the activities of AP C3 and C5 convertases, Ruxoprubart effectively inhibits red blood cell hemolysis and reduces C3b deposition, thereby preventing intravascular and extravascular hemolysis. Ruxoprubart can be used in research related to paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, C3 glomerulopathy, and IgA nephropathy.

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  • Pureté: 95.541%
  • CAS No.: 2842046-67-5
  • Masse moléculaire:145.982 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ruxoprubart
  • Experimental Validation Results for Ruxoprubart
  • Ruxoprubart Chemical Structure
    Ruxoprubart Chemical Structure
CAS No.: 2842046-67-5
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Ruxoprubart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized Complement Factor B/CFB Protein, Human (HEK293, His, HY-P7813) can bind Ruxoprubart. The EC50 for this effect is 24.9 ng/mL.

  • Ruxoprubart Chemical Structure
    1/16
  • Ruxoprubart
  • Immobilized Complement Factor B/CFB Protein, Human (HEK293, His, HY-P7813) can bind Ruxoprubart. The EC50 for this effect is 24.9 ng/mL.
  • IgG1-kappa