SAFit2 (Standard)
SAFit2 (Standard) is the analytical standard of SAFit2 (HY-102080). This product is intended for research and analytical applications. SAFit2, a chemical probe, is a highly potent, highly selective FK506-binding protein 51 (FKBP51) inhibitor with a Ki of 6 nM and also enhances AKT2-AS160 binding.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 1643125-33-0
- Formule: C46H62N2O10
- Masse moléculaire:802.99
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-102080
SAFit2FKBP51 Inhibitor -
HY-112210
Shield-1FKBP Ligand -
HY-114434
AP1867FKBP12F36V-directed Ligand -
HY-102079
SAFit1 -
HY-13992
AP20187FKBP Dimerizer -
HY-114872
SLFFKBP Ligand -
HY-107452
SLF-amido-C2-COOHFKBP Ligand -
HY-114420
AP1867-2-(carboxymethoxy)Ligands for Target Protein for PROTAC -
HY-126316
Zapalog -
HY-102079R
SAFit1 (Standard)Reference Standard -
HY-135345
PROTAC FKBP Degrader-3FKBP PROTAC Degrader -
HY-153806
RapaBlockFKBP12 Ligand
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1643125-33-0
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Masse moléculaire 802.99
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Formule C46H62N2O10
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SMILES
O=C(N1[C@@H](CCCC1)C(O[C@@H](C2=CC(OCCN3CCOCC3)=CC=C2)CCC4=CC(OC)=C(OC)C=C4)=O)[C@@H](C5CCCCC5)C6=CC(OC)=C(OC)C(OC)=C6
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Gaali S, et al. Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51. J Med Chem. 2016 Mar 24;59(6):2410-22. [Content Brief]
[2]. Balsevich G, et al. Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. Nat Commun. 2017 Nov 23;8(1):1725. [Content Brief]
[3]. Hartmann J, et al. Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties. J Neurosci. 2015 Jun 17;35(24):9007-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SAFit2 (Standard) Related Classifications
HY-102080R Related Classifications
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