SCH 54388
SCH 54388 is an orally active metabolite of Felbamate (HY-B0184). SCH 54388 significantly attenuates the functional impairment effects induced by Scopolamine (HY-N0296) or Dizocilpine (HY-15084B). SCH 54388 can be used in research related to cognitive impairment.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 25451-53-0
- Formule: C10H13NO3
- Masse moléculaire:195.22
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
SCH 54388 (0.01-0.1 mg/kg; s.c.; single administration) reverses dizocilpine-induced cognitive impairment in CF-1 mice[1].
SCH 54388 (10-100 mg/kg; s.c.; single administration) produces statistically significant analgesic effects in CF-1 mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Charles River BALB (male, 25-30 g, scopolamine-induced cognitive impairment)[1]
-
Dosage:0.1 mg/kg; 1.0 mg/kg; 10 mg/kg
-
Administration:s.c.; single dose
-
Result:Produced mean reentry latencies statistically greater than scopolamine alone.
Demonstrated a statistically significant overall treatment effect.
-
Animal Model:Charles River BALB (male, 25-30 g, scopolamine-induced cognitive impairment)[1]
-
Dosage:0.1 mg/kg; 1.0 mg/kg; 10 mg/kg
-
Administration:p.o.; single dose
-
Result:Produced mean reentry latencies statistically greater than scopolamine alone.
Demonstrated a statistically significant overall treatment effect.
-
Animal Model:Charles River CF-1 (male, 25-30 g, dizocilpine-induced cognitive impairment)[1]
-
Dosage:0.01 mg/kg; 0.1 mg/kg
-
Administration:s.c.; single dose
-
Result:Produced mean reentry latencies statistically greater than dizocilpine alone.
Demonstrated a statistically significant overall treatment effect.
-
Animal Model:Charles River CF-1 (male, 25-30 g)[1]
-
Dosage:10 mg/kg; 100 mg/kg
-
Administration:s.c.; single dose
-
Result:Produced statistically significant increases in mean escape jump latencies compared to vehicle-treated animals.
Chemical Information
-
CAS No. 25451-53-0
-
Masse moléculaire 195.22
-
Formule C10H13NO3
-
SMILES
O=C(N)OCC(CO)C1=CC=CC=C1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SCH 54388 Related Classifications
HY-123280 Related Classifications
Powered by Bioz