16 Results for "

VIPR

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "VIPR" in MCE Product Catalog:

Cat. No.: HY-P6292A
Target:  

PACAP Receptor

KS-133 TFA is a highly selective and potent antagonist of the vascular active enteropeptide receptor 2 (VIPR2) with IC50 values for Ca influx measurement and cAMP measurement of 24.8 nM and 500 nM, respectively. KS-133 TFA reverses the tumor-promoting M2 phenotype of tumor-associated macrophages to the anti-tumor M1 phenotype, alters the tumor immune microenvironment, and inhibits tumor growth. KS-133 TFA can be used for research on schizophrenia and cancer immune regulation .
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Cat. No.: HY-P6292
CAS No.: 2724212-01-3
Domaines de recherche:  

Neurological Disease Cancer

KS-133 is a bicyclic peptide with VIPR2 antagonistic activity that can cross the blood-brain barrier. KS-133 selectively blocks VIPR2-mediated Gq/Ca, Gs/cAMP, cAMP/PKA/ERK and PI3K/AKT/GSK3β signaling pathways. KS-133 inhibits VIPR2 agonist-induced CREB phosphorylation in the prefrontal cortex of mice. KS-133 shifts the polarization direction of macrophages toward M1. KS-133 attenuates cancer cell proliferation and reduces the cell cycle distribution level at the S-M phase. KS-133 exerts antitumor effects in a mouse model of colorectal cancer. KS-133 reverses cognitive decline in mouse models of psychiatric disorders. KS-133 can be used for research related to schizophrenia, colorectal cancer and breast cancer .
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Cat. No.: HY-103528
CAS No.: 3232-36-8
Pureté:  99.64%
Synonyms: Salicylidene salicylhydrazide
Target:  

GABA Receptor

Domaines de recherche:  

Neurological Disease Inflammation/Immunology

SCS (Salicylidene salicylhydrazide) is a potent, allosteric and selective inhibitor of β1-containing GABAA receptors with an IC50 of 32 nM against α2β1γ1θ by VIPR measurement. SCS is also a chelator of metal ions .
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Cat. No.: HY-RS15655
Domaines de recherche:  

Others

VIPR1 Human Pre-designed siRNA Set A contains three designed siRNAs for VIPR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS15656
Domaines de recherche:  

Others

VIPR2 Human Pre-designed siRNA Set A contains three designed siRNAs for VIPR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS18849
Domaines de recherche:  

Others

Vipr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vipr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS22914
Domaines de recherche:  

Others

Vipr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vipr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS25341
Domaines de recherche:  

Others

Vipr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Vipr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS29428
Domaines de recherche:  

Others

Vipr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Vipr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Cat. No.: HY-P81524
Synonyms: vasoactive inTinal peptide receptor 1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81524A
Synonyms: vasoactive inTinal peptide receptor 1; II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P76128
Pureté:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Vasoactive intestinal polypeptide receptor 2; VIP-R-2; PACAP-R3; VPAC2; VIPR2
Species:  
Source:  
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Cat. No.: HY-103528R
CAS No.: 3232-36-8
Synonyms: Salicylidene salicylhydrazide (Standard)
SCS (Standard) is the analytical standard of SCS (HY-103528). This product is intended for research and analytical applications. SCS (Salicylidene salicylhydrazide) is a potent, allosteric and selective inhibitor of β1-containing GABAA receptors with an IC50 of 32 nM against α2β1γ1θ by VIPR measurement. SCS is also a chelator of metal ions .
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Cat. No.: HY-121837
CAS No.: 2088234-50-6
β2AR-IN-15 is a selective β2-adrenergic receptor (β2AR) antagonist with a Kd of 1.7 μM. β2AR-IN-15 binds to an intracellular β2AR region overlapping the G-protein binding site, enhancing orthosteric inverse agonist binding while negatively modulating binding of orthosteric agonists with EC50 values of 1.9 and 0.48 μM. β2AR-IN-15 shows inhibitory effect on cAMP production and β-arrestin recruitment to activated β2AR. β2AR-IN-15 can be used for the research of cardiovascular and pulmonary diseases .
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Cat. No.: HY-P81526
Synonyms: VIP2R; VIPR2; Vasoactive intestinal polypeptide receptor 2; VIP-R-2; Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor (PACAP type III receptor; PACAP-R-3; PACAP-R3); VPAC2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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Cat. No.: HY-P81526A
Synonyms: VIP2R; VIPR2; Vasoactive intestinal polypeptide receptor 2; VIP-R-2; Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor (PACAP type III receptor; PACAP-R-3; PACAP-R3); VPAC2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

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