1005275-19-3
1005275-19-3
Chemical Structure
KLHDC2-IN-1
- CAS. Nr.: 1005275-19-3
- Formula:C22H19ClF3NO3
- Molecular Weight:437.84
SMILES: OC(C1=C2C(C(C3CCC4C3)C4C(C5=CC(OC(F)(F)F)=CC=C5)N2)=CC(Cl)=C1)=O
Biological Activity: KLHDC2-IN-1 (Compound 6) is a ligand targeting the ubiquitin E3 ligase KLHDC2 (Kd: 160 nM). KLHDC2-IN-1 enables the synthesis of a PROTAC that can effectively degrade BRD4 in cells[1].
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KLHDC2-IN-1 | KLHDC2-IN-1 (Compound 6) is a ligand targeting the ubiquitin E3 ligase KLHDC2 (Kd: 160 nM). KLHDC2-IN-1 enables the synthesis of a PROTAC that can effectively degrade BRD4 in cells. | |||||||||||||||||||||
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References
Keywords
