KLHDC2-IN-1
KLHDC2-IN-1 (Compound 6) is a ligand targeting the ubiquitin E3 ligase KLHDC2 (Kd: 160 nM). KLHDC2-IN-1 enables the synthesis of a PROTAC that can effectively degrade BRD4 in cells.
For research use only. We do not sell to patients.
- CAS No.: 1005275-19-3
- Formula: C22H19ClF3NO3
- Molecular Weight:437.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1005275-19-3
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Molecular Weight 437.84
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Formula C22H19ClF3NO3
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SMILES
OC(C1=C2C(C(C3CCC4C3)C4C(C5=CC(OC(F)(F)F)=CC=C5)N2)=CC(Cl)=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)