10141-51-2
Chemical Structure
CP-24879 hydrochloride
- CAS No.: 10141-51-2
- Formula:C11H18ClNO
- Molecular Weight:215.72
IUPAC Name: 4-(isopentyloxy)aniline hydrochloride
InChIKey: GFESZSNFRSACMU-UHFFFAOYSA-N
SMILES: NC1=CC=C(OCCC(C)C)C=C1.Cl
Biological Activity: CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research[1][2].
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CP-24879 hydrochloride | 99.59% | CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research. | ||||||||||||||||||||
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Similarity Score 0.80
HY-N61492-Isobutoxyaniline -
Similarity Score 0.77
HY-W096113m-PEG2-O-Ph-NH2 -
Similarity Score 0.76
HY-302714-Butoxyphenol -
Similarity Score 0.75
HY-W027691A3-(Prop-2-yn-1-yloxy)aniline hydrochloride -
Similarity Score 0.75
HY-444082-(4-Bromophenoxy)ethanol -
Similarity Score 0.75
HY-W0168572-(4-Chlorophenoxy)ethanol -
Similarity Score 0.75
HY-W017186ALDH1A3-IN-3 -
Similarity Score 0.74
HY-W096118m-PEG2-O-Ph-3-NH2 -
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References
- [1]. Obukowicz MG, et al. Identification and characterization of a novel delta6/delta5 fatty acid desaturase inhibitor as a potential anti-inflammatory agent. Biochem Pharmacol. 1998 Apr 1;55(7):1045-58. [Content Brief]
- [2]. [2]López-Vicario C, et al. Molecular interplay between Δ5/Δ6 desaturases and long-chain fatty acids in the pathogenesis of non-alcoholic steatohepatitis. Gut. 2014 Feb;63(2):344-55. [Content Brief]
