101843-93-0
101843-93-0
Chemical Structure
7-Deazaneplanocin A
- CAS No.: 101843-93-0
- Formula:C12H14N4O3
- Molecular Weight:262.26
InChIKey: LNNHUAXCDFXQNM-BBBLOLIVSA-N
SMILES: NC1=NC=NC2=C1C=CN2[C@H]3[C@H](O)[C@H](O)C(CO)=C3
Biological Activity: 7-Deazaneplanocin A is a carbocyclic nucleoside analog with anti-HCV activity and anti-HBV activity (EC50 0.60 µM). 7-Deazaneplanocin A exhibits activity against vaccinia virus and variola virus in vitro, with low cytotoxicity. 7-Deazaneplanocin A is applicable to studies related to viral infections[1][2].
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7-Deazaneplanocin A | 7-Deazaneplanocin A is a carbocyclic nucleoside analog with anti-HCV activity and anti-HBV activity (EC50 0.60 µM). 7-Deazaneplanocin A exhibits activity against vaccinia virus and variola virus in vitro, with low cytotoxicity. 7-Deazaneplanocin A is applicable to studies related to viral infections. | |||||||||||||||||||||
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References
- [1]. Kim HJ, et al. Synthesis and anti-hepatitis B virus and anti-hepatitis C virus activities of 7-deazaneplanocin A analogues in vitro. Journal of medicinal chemistry. 2009 Jan 08;52(1):206-13. [Content Brief]
- [2]. Arumugham B, et al. Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus). Bioorganic & medicinal chemistry letters. 2006 Jan 15;16(2):285-7. [Content Brief]
