1020567-30-9
1020567-30-9
Chemical Structure
GSK2324
- CAS No.: 1020567-30-9
- Formula:C29H22Cl2N2O4
- Molecular Weight:533.40
IUPAC Name: 6-(4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)phenyl)quinoline-2-carboxylic acid
InChIKey: SZUHDKKQQZPOGX-UHFFFAOYSA-N
SMILES: O=C(C1=NC2=CC=C(C3=CC=C(OCC4=C(C(C)C)ON=C4C5=C(Cl)C=CC=C5Cl)C=C3)C=C2C=C1)O
Biological Activity: GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively[1].
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GSK2324 | GSK2324 (Compd 1c) is a FXR agonist for diabetes study, with an EC50 of 120 nM. GSK2324 exhibits t1/2 values of 84 min (mouse), 170 min (rat), 110 min (beagle) and 120 min (cyno), respectively. | |||||||||||||||||||||
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References
Keywords
