1021707-76-5
Chemical Structure
CU-2010
- CAS No.: 1021707-76-5
- Formula:C37H42N6O6S
- Molecular Weight:698.83
InChIKey: BHQDUYVBGREBCB-SAIUNTKASA-N
SMILES: NCC1=CC=CC(C[C@@H](C(NCC2=CC=C(C=C2)C(N)=N)=O)NC([C@@H](CCCC3=CC=CC=C3)NS(CC4=CC(C(O)=O)=CC=C4)(=O)=O)=O)=C1
Biological Activity: CU-2010 is a synthetic low-molecular-weight serine protease inhibitor with anticoagulant, antifibrinolytic, anti-inflammatory, and cardioprotective properties. CU-2010 inhibits plasma kallikrein, factor Xa, and factor XIa activity. CU-2010 reduces free radical generation, lipid peroxidation, and postoperative blood loss; improves postischemic myocardial contractility, coronary blood flow, and endothelium-dependent vasodilatation; prolongs clotting and clot lysis times; and preserves clot firmness. CU-2010 can be used for the research of postoperative blood loss and postischemic myocardial dysfunction after cardiac surgery with cardiopulmonary bypass[1].
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CU-2010 | CU-2010 is a synthetic low-molecular-weight serine protease inhibitor with anticoagulant, antifibrinolytic, anti-inflammatory, and cardioprotective properties. CU-2010 inhibits plasma kallikrein, factor Xa, and factor XIa activity. CU-2010 reduces free radical generation, lipid peroxidation, and postoperative blood loss; improves postischemic myocardial contractility, coronary blood flow, and endothelium-dependent vasodilatation; prolongs clotting and clot lysis times; and preserves clot firmness. CU-2010 can be used for the research of postoperative blood loss and postischemic myocardial dysfunction after cardiac surgery with cardiopulmonary bypass. | |||||||||||||||||||||
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