10231-84-2
Chemical Structure
p-Nitrophenyl α-L-fucoside
Synonym(s): PNP α-L-Fuc
- CAS. Nr.: 10231-84-2
- Formula:C12H15NO7
- Molecular Weight:285.25
IUPAC Name: (2S,3S,4R,5S,6S)-2-methyl-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: YILIDCGSXCGACV-SQKFTNEHSA-N
SMILES: O[C@@H]([C@@H]([C@@H]([C@H](C)O1)O)O)[C@@H]1OC2=CC=C([N+]([O-])=O)C=C2
Biological Activity: p-Nitrophenyl α-L-fucoside (PNP α-L-Fuc) is a specific substrate of Pecten maximus α-L-fucosidase, with a Km value of 650 µM. p-Nitrophenyl α-L-fucoside serves as a substrate for ClAgl29A and ClAgl29B. Enzymatic hydrolysis of p-Nitrophenyl α-L-fucoside releases p-nitrophenol and α-L-fucose, where the latter undergoes mutarotation over time to form β-L-fucose. p-Nitrophenyl α-L-fucoside is not the preferred substrate for ClAgl29A and ClAgl29B[1][2][3].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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p-Nitrophenyl α-L-fucoside | 98.80% | p-Nitrophenyl α-L-fucoside (PNP α-L-Fuc) is a specific substrate of Pecten maximus α-L-fucosidase, with a Km value of 650 µM. p-Nitrophenyl α-L-fucoside serves as a substrate for ClAgl29A and ClAgl29B. Enzymatic hydrolysis of p-Nitrophenyl α-L-fucoside releases p-nitrophenol and α-L-fucose, where the latter undergoes mutarotation over time to form β-L-fucose. p-Nitrophenyl α-L-fucoside is not the preferred substrate for ClAgl29A and ClAgl29B. | ||||||||||||||||||||
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References
- [1]. Shishiuchi R, et al. Discovery of α-l-Glucosidase Raises the Possibility of α-l-Glucosides in Nature. ACS Omega. 2022;7(50):47411-47423. Published 2022 Dec 9. [Content Brief]
- [2]. Berteau O, et al. Characterization of a new alpha-L-fucosidase isolated from the marine mollusk Pecten maximus that catalyzes the hydrolysis of alpha-L-fucose from algal fucoidan (Ascophyllum nodosum). Glycobiology. 2002;12(4):273-282. [Content Brief]
- [3]. Miura T, et al. Purification and characterization of extracellular 1,2-alpha-L-fucosidase from Bacillus cereus. J Biosci Bioeng. 2005;99(6):629-635. [Content Brief]
