1030612-87-3
1030612-87-3
Chemical Structure
MK-8245 analog
- CAS No.: 1030612-87-3
- Formula:C16H15BrFN7O3S
- Molecular Weight:484.30
IUPAC Name: 2-(5-(5-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid
InChIKey: SVTBUTPWEOUGGT-UHFFFAOYSA-N
SMILES: O=C(O)CN1N=C(C2=NN=C(N3CCC(OC4=CC(F)=CC=C4Br)CC3)S2)N=N1
Biological Activity: MK-8245 analog (compound 6) is a potent stearoyl-CoA desaturase (SCD) inhibitor with an IC50 of 7 nM for rat SCD. MK-8245 analog has antidiabetic and antidyslipidemic effects[1].
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MK-8245 analog | MK-8245 analog (compound 6) is a potent stearoyl-CoA desaturase (SCD) inhibitor with an IC50 of 7 nM for rat SCD. MK-8245 analog has antidiabetic and antidyslipidemic effects. | |||||||||||||||||||||
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References
Keywords
