1031496-06-6
Chemical Structure
CIM0216
- CAS No.: 1031496-06-6
- Formula:C21H21N3O2
- Molecular Weight:347.41
IUPAC Name: 2-(3,4-dihydroquinolin-1(2H)-yl)-N-(5-methylisoxazol-3-yl)-2-phenylacetamide
InChIKey: KSEXDSJYVSEVGF-UHFFFAOYSA-N
SMILES: CC1=CC(NC(C(C2=CC=CC=C2)N3C4=CC=CC=C4CCC3)=O)=NO1
Biological Activity: CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research[1].
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CIM0216 | 99.94% | CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research. | ||||||||||||||||||||
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Keywords
