103239-14-1
Chemical Structure
12(S)-HPEPE
- CAS No.: 103239-14-1
- Formula:C20H30O4
- Molecular Weight:334.45
IUPAC Name: (S,5Z,8Z,10E,14Z,17Z)-12-hydroperoxyicosa-5,8,10,14,17-pentaenoic acid
InChIKey: HDMYXONNVAOHFR-UOLHMMFFSA-N
SMILES: CC/C=C\C/C=C\C[C@H](OO)/C=C/C=C\C/C=C\CCCC(O)=O
Biological Activity: 12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells[1].
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12(S)-HPEPE | 12(S)-HPEPE is a lipoxygenase product and an intermediate metabolite that leads to downregulation of PGHS-2 and has potential anti-inflammatory activity. 12(S)-HPEPE reduces interleukin 1h (IL-1h)-induced PGHS-2 expression in human lung microvascular endothelial cells. | |||||||||||||||||||||
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Keywords