103370-21-4
Chemical Structure
KS 619-1
- CAS No.: 103370-21-4
- Formula:C26H18O9
- Molecular Weight:474.42
IUPAC Name: 1,7,9,11-tetrahydroxy-8,13-dioxo-3-(2-oxopropyl)-5,6,8,13-tetrahydrobenzo[a]tetracene-2-carboxylic acid
InChIKey: ODDJKDDLIBUZMH-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(O)C=2C3=CC=4C(=O)C=5C=C(O)C=C(O)C5C(=O)C4C(O)=C3CCC2C=C1CC(=O)C
Biological Activity: KS 619-1 is a Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase inhibitor. KS 619-1 exhibits strong inhibitory activity against this enzyme derived from bovine brain and heart, but shows weak inhibitory effects on calmodulin-independent phosphodiesterase and protein kinase C. KS 619-1 displays weak antibacterial activity against Staphylococcus aureus[1].
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KS 619-1 | KS 619-1 is a Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase inhibitor. KS 619-1 exhibits strong inhibitory activity against this enzyme derived from bovine brain and heart, but shows weak inhibitory effects on calmodulin-independent phosphodiesterase and protein kinase C. KS 619-1 displays weak antibacterial activity against Staphylococcus aureus. | |||||||||||||||||||||
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