104051-69-6
Chemical Structure
Tosufloxacin hydrochloride
Synonym(s): A-61827 hydrochloride
- CAS No.: 104051-69-6
- Formula:C19H16ClF3N4O3
- Molecular Weight:440.80
IUPAC Name: 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid hydrochloride
InChIKey: CIHZSSCESOLBRQ-UHFFFAOYSA-N
SMILES: FC1=CC(F)=C(C=C1)N2C=C(C(C3=C2N=C(C(F)=C3)N4CCC(C4)N)=O)C(O)=O.Cl
Biological Activity: Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria[1][2].
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Tosufloxacin hydrochloride | Tosufloxacin (A-61827) hydrochloride is an orally active fluoroquinolone antibiotic. Tosufloxacin hydrochloride shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria. | |||||||||||||||||||||
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- [1]. Chu DT, et al. Synthesis and biological properties of A-71497: a prodrug of tosufloxacin. Drugs Exp Clin Res. 1990;16(9):435-43. [Content Brief]
- [2]. Fujimaki K, et al. In vitro and in vivo antibacterial activities of T-3262, a new fluoroquinolone. Antimicrob Agents Chemother. 1988 Jun;32(6):827-33. [Content Brief]
Keywords
