1044663-62-8
Chemical Structure
Topotecan hydrochloride hydrate
Synonym(s): SKF 104864A hydrochloride hydrate; NSC 609669 hydrochloride hydrate
- CAS No.: 1044663-62-8
- Formula:C23H26ClN3O6
- Molecular Weight:475.92
IUPAC Name: (S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione hydrochloride hydrate
InChIKey: XVYBIGDRQOMVJX-IFUPQEAVSA-N
SMILES: O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(CN(C)C)C(O)=CC=C5N=C4C3=C2)=O.Cl.O
Biological Activity: Topotecan hydrochloride hydrate is an orally active and potent Topoisomerase I inhibitor. Topotecan hydrochloride hydrate induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan hydrochloride hydrate shows anticancer activity[1].
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Topotecan hydrochloride hydrate | Topotecan hydrochloride hydrate is an orally active and potent Topoisomerase I inhibitor. Topotecan hydrochloride hydrate induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan hydrochloride hydrate shows anticancer activity. | |||||||||||||||||||||
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