1048668-70-7
Chemical Structure
AZD8329
- CAS No.: 1048668-70-7
- Formula:C25H31N3O3
- Molecular Weight:421.53
IUPAC Name: 4-(4-(adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid
InChIKey: XWBXJBSVYVJAMZ-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(N2N=CC(C(NC3C(C4)CC5CC4CC3C5)=O)=C2C(C)(C)C)C=C1
Biological Activity: AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].
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AZD8329 | 99.68% | AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3. | ||||||||||||||||||||
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Keywords