1048668-70-7
1048668-70-7
Chemical Structure
AZD8329
- CAS No.: 1048668-70-7
- Formula:C25H31N3O3
- Molecular Weight:421.53
IUPAC Name: 4-(4-(adamantan-2-ylcarbamoyl)-5-(tert-butyl)-1H-pyrazol-1-yl)benzoic acid
InChIKey: XWBXJBSVYVJAMZ-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(N2N=CC(C(NC3C(C4)CC5CC4CC3C5)=O)=C2C(C)(C)C)C=C1
Biological Activity: AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZD8329 | 99.68% | AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.55
HY-163769DUB-IN-8 -
Similarity Score 0.45
HY-W4565721-(4-Carboxyphenyl)-1H-pyrazole-4-carboxylic acid -
Similarity Score 0.44
HY-171460Win 45164 -
Similarity Score 0.44
HY-1148942C07 -
Similarity Score 0.44
HY-138668JW-65 -
Similarity Score 0.44
HY-175238KI-DX-014 -
Similarity Score 0.44
HY-135674SR-318 -
Similarity Score 0.44
HY-W4565861-(4-Carboxyphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid -
Similarity Score 0.43
HY-105064AZoniporide mesylate -
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