10527-46-5
10527-46-5
Chemical Structure
Ap4G
- CAS No.: 10527-46-5
- Formula:C20H28N10O20P4
- Molecular Weight:852.39
InChIKey: SJXJAXXRDJWRCR-INFSMZHSSA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1COP(OP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C=NC6=C5N=CN=C6N)O4)(O)=O)(O)=O)(O)=O)(O)=O
Biological Activity: Ap4G is a dinucleoside polyphosphate compound with vasoconstrictor activity. Ap4G regulates vasoconstriction through P2 receptors, especially P2X receptors, and is an important tool for studying vascular physiology and pathology[1].
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Ap4G | Ap4G is a dinucleoside polyphosphate compound with vasoconstrictor activity. Ap4G regulates vasoconstriction through P2 receptors, especially P2X receptors, and is an important tool for studying vascular physiology and pathology. | |||||||||||||||||||||
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References
- [1]. Ralevic V, et al. Structure‐activity relationships of diadenosine polyphosphates (ApnAs), adenosine polyphospho guanosines (ApnGs) and guanosine polyphospho guanosines (GpnGs) at P2 receptors in the rat mesenteric arterial bed[J]. British journal of pharmacology, 2001, 134(5): 1073-1083. [Content Brief]
