1056636-06-6
1056636-06-6
Chemical Structure
Momelotinib sulfate
Synonym(s): CYT387 sulfate salt
- CAS No.: 1056636-06-6
- Formula:C23H26N6O10S2
- Molecular Weight:610.62
IUPAC Name: N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide bis(sulfate)
InChIKey: XJGPMRGWDSQVTN-UHFFFAOYSA-N
SMILES: O=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2.O=S(O)(O)=O.O=S(O)(O)=O
Biological Activity: Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Momelotinib sulfate | 98.45% | Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). | ||||||||||||||||||||
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Momelotinib sulfate (Standard) | ≥98% | Momelotinib (sulfate) (Standard) is the analytical standard of Momelotinib (sulfate). This product is intended for research and analytical applications. Momelotinib sulfate (CYT387 sulfate salt) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, 10-fold selectivity versus JAK3 (IC50=155 nM). | ||||||||||||||||||||
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