106498-99-1
106498-99-1
Chemical Structure
Vintoperol
Synonym(s): RGH 2981; RT-3003
- CAS No.: 106498-99-1
- Formula:C18H24N2O
- Molecular Weight:284.40
IUPAC Name: ((1S,12bS)-1-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-1-yl)methanol
InChIKey: BKRBRZLECKMEBD-QZTJIDSGSA-N
SMILES: CC[C@]1([C@@]2([H])C3=C(CCN2CCC1)C4=CC=CC=C4N3)CO
Biological Activity: Vintoperol (RGH 2981; RT-3003) is a potent and orally active antithrombotic agent. Vintoperol interferes with platelet aggregation and has antithrombotic effects, protecting mice from retrograde and anterograde amnesia induced by traumatic brain injury[1][2].
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Vintoperol | Vintoperol (RGH 2981; RT-3003) is a potent and orally active antithrombotic agent. Vintoperol interferes with platelet aggregation and has antithrombotic effects, protecting mice from retrograde and anterograde amnesia induced by traumatic brain injury. | |||||||||||||||||||||
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References
- [1]. Froestl W, et al. Cognitive enhancers (nootropics). Part 1: drugs interacting with receptors. J Alzheimers Dis. 2012;32(4):793-887. [Content Brief]
- [2]. Yoshitsugu H, et al. Key fragments for identification of positional isomer pair in glucuronides from the hydroxylated metabolites of RT-3003 (Vintoperol) by liquid chromatography/electrospray ionization mass spectrometry. J Mass Spectrom. 1999 Oct;34(10):1063-8. [Content Brief]
Keywords
