1065606-97-4
Chemical Structure
AR453588 hydrochloride
- CAS No.: 1065606-97-4
- Formula:C25H26ClN7O2S2
- Molecular Weight:556.10
IUPAC Name: 1-(4-(5-((3-((2-methylpyridin-3-yl)oxy)-5-(pyridin-2-ylthio)pyridin-2-yl)amino)-1,2,4-thiadiazol-3-yl)piperidin-1-yl)ethan-1-one hydrochloride
InChIKey: DVXDJNBGXCILIU-UHFFFAOYSA-N
SMILES: CC(N1CCC(C2=NSC(NC3=NC=C(SC4=NC=CC=C4)C=C3OC5=CC=CN=C5C)=N2)CC1)=O.[H]Cl
Biological Activity: AR453588 hydrochloride is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 hydrochloride shows anti-hyperglycemic activity[1].
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AR453588 hydrochloride | AR453588 hydrochloride is a potent and orally bioavailable anti-diabetic glucokinase activator, with an EC50 of 42 nM. AR453588 hydrochloride shows anti-hyperglycemic activity. | |||||||||||||||||||||
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Keywords