106614-68-0
106614-68-0
Chemical Structure
(Rac)-Amorolfine hydrochloride
- CAS No.: 106614-68-0
- Formula:C21H36ClNO
- Molecular Weight:353.97
IUPAC Name: 2,6-dimethyl-4-(2-methyl-3-(4-(tert-pentyl)phenyl)propyl)morpholine hydrochloride
InChIKey: XZKWIPVTHGWDCF-UHFFFAOYSA-N
SMILES: CC1OC(CN(C1)CC(CC2=CC=C(C=C2)C(C)(CC)C)C)C.Cl
Biological Activity: (Rac)-Amorolfine hydrochloride is the racemic form of Amorolfine hydrochloride. Amorolfine (Ro 14-4767/002) hydrochloride (HY-B0238) is an effective antifungal agent. Amorolfine hydrochloride inhibits the biosynthesis of ergosterol and has research potential for treating onychomycosis caused by Neoscytalidium dimidiatum[1][2].
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(Rac)-Amorolfine hydrochloride | (Rac)-Amorolfine hydrochloride is the racemic form of Amorolfine hydrochloride. Amorolfine (Ro 14-4767/002) hydrochloride (HY-B0238) is an effective antifungal agent. Amorolfine hydrochloride inhibits the biosynthesis of ergosterol and has research potential for treating onychomycosis caused by Neoscytalidium dimidiatum. | |||||||||||||||||||||
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References
- [1]. Haria M, et al. Amorolfine. A review of its pharmacological properties and therapeutic potential in the treatment of onychomycosis and other superficial fungal infections. Drugs. 1995 Jan;49(1):103-20. [Content Brief]
- [2]. Bunyaratavej S, et al. Efficacy of 5% amorolfine nail lacquer in Neoscytalidium dimidiatum onychomycosis. J Dermatolog Treat. 2016 Aug;27(4):359-63. [Content Brief]
