1076225-27-8
1076225-27-8
Chemical Structure
PF-998425
- CAS No.: 1076225-27-8
- Formula:C14H14F3NO
- Molecular Weight:269.26
IUPAC Name: 4-((1R,2R)-2-hydroxycyclohexyl)-2-(trifluoromethyl)benzonitrile
InChIKey: MENRRRXHFQYXDW-DGCLKSJQSA-N
SMILES: O[C@H]1[C@H](CCCC1)C2=CC(C(F)(F)F)=C(C=C2)C#N
Biological Activity: PF-998425 is a potent, selective nonsteroidal androgen receptor (AR) antagonist with an IC50 of 37 nM and 43 nM in AR binding and cellular assays, respectively. PF-998425 has low activity on common receptors and enzymes, such as progesterone receptor. PF-998425 can be used for sebum control and androgenetic alopecia research[1].
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PF-998425 | 98.0% | PF-998425 is a potent, selective nonsteroidal androgen receptor (AR) antagonist with an IC50 of 37 nM and 43 nM in AR binding and cellular assays, respectively. PF-998425 has low activity on common receptors and enzymes, such as progesterone receptor. PF-998425 can be used for sebum control and androgenetic alopecia research. | ||||||||||||||||||||
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