108307-65-9

RB-90740 Chemical Structure
108307-65-9

Chemical Structure

RB-90740

  • CAS 番号: 108307-65-9
  • Formula:C20H22N6O
  • Molecular Weight:362.43

IUPAC Name: 2-(4-methylpiperazin-1-yl)-6-phenyl-8,9-dihydroimidazo[1,2-a]pyrido[3,2-e]pyrazine 5-oxide

InChIKey: CKRPRSXFNWNTOW-UHFFFAOYSA-N

SMILES: CN1CCN(CC1)C2=CC=C3[N+]([O-])=C(C4=NCCN4C3=N2)C5=CC=CC=C5

Biological Activity: RB-90740 is a type of biological reducing agent. RB-90740 is activated through metabolic reduction and generates cytotoxic products, thereby selectively killing tumor cells (usually in a hypoxic environment). RB-90740 has selective toxicity towards hypoxic cells, which is mainly achieved by causing DNA strand breaks and activating reducing enzymes (such as Cytochrome P450). RB-90740 does not initially exhibit cytotoxicity similar to its in vitro properties in hypoxic cells in mouse models. RB-90740 can be used to study the tumor physiological environment[1][2]

製品番号 製品名 純度 製品説明 Pricing
HY-118722
RB-90740 RB-90740 is a type of biological reducing agent. RB-90740 is activated through metabolic reduction and generates cytotoxic products, thereby selectively killing tumor cells (usually in a hypoxic environment). RB-90740 has selective toxicity towards hypoxic cells, which is mainly achieved by causing DNA strand breaks and activating reducing enzymes (such as Cytochrome P450). RB-90740 does not initially exhibit cytotoxicity similar to its in vitro properties in hypoxic cells in mouse models. RB-90740 can be used to study the tumor physiological environment
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