109194-60-7
Chemical Structure
Tachioside
- CAS. Nr.: 109194-60-7
- Formula:C13H18O8
- Molecular Weight:302.28
IUPAC Name: (2S,3R,4S,5S,6R)-2-(4-hydroxy-3-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChIKey: KWVHACHAQJFTLZ-UJPOAAIJSA-N
SMILES: O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC=C(O)C(OC)=C2
Biological Activity: Tachioside is a phenolic glycoside natural product. Tachioside inhibits antigen-induced mast cell degranulation and TNF-α expression in RBL-2H3 cells; it exhibits melanin inhibitory effects in B16 melanoma cells. Tachioside possesses anti-obesity, antioxidant, and α-glucosidase inhibitory activities. Tachioside has been predicted as a potential anti-breast cancer candidate compound and shows high correlation coefficients with antioxidant indicators such as ABTS and FRAP. Tachioside can be used in research on allergies and pigmentation-related diseases[1][2][3][4][5][6][7].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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Tachioside | 99.69% | Tachioside is a phenolic glycoside natural product. Tachioside inhibits antigen-induced mast cell degranulation and TNF-α expression in RBL-2H3 cells; it exhibits melanin inhibitory effects in B16 melanoma cells. Tachioside possesses anti-obesity, antioxidant, and α-glucosidase inhibitory activities. Tachioside has been predicted as a potential anti-breast cancer candidate compound and shows high correlation coefficients with antioxidant indicators such as ABTS and FRAP. Tachioside can be used in research on allergies and pigmentation-related diseases. | ||||||||||||||||||||
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References
- [1]. Lee JY, et al. Wheat Bran Extract Regulates Mast Cell-Mediated Allergic Responses In Vitro and In Vivo. Molecules (Basel, Switzerland). 2020 Sep 02;25(17):3997.
- [2]. Annisa Y, et al. Integrated In vitro And In silico Exploration of Bioactive Compounds in Strychnos lucida Stem Extract: Revealing Mechanisms Against Breast Cancer. Trends in Sciences. 2025 May 10;22(6):9940-.
- [3]. Wang J, et al. Comparative analysis of phytochemical profile and antioxidant and anti-inflammatory activity of four Gentiana species from the Qinghai-Tibet Plateau. Journal of ethnopharmacology. 2024 May 23;326:117926.
- [4]. Andrade JM, et al. Evidence of Antiproliferative Activity in the Liverwort Isotachis serrulata from Southern Ecuador. Molecules. 2026 Apr 6;31(7):1208.
- [5]. Ashour A, et al. Melanin synthesis inhibition activity of compounds isolated from bamboo shoot skin (phyllostachys pubescens). Molecules. 2022 Dec 20;28(1):23.
- [6]. Luyen BT, et al. A new phenylpropanoid and an alkylglycoside from Piper retrofractum leaves with their antioxidant and α-glucosidase inhibitory activity. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4120-4. [Content Brief]
- [7]. Tian EL, et al. Phenolic glycosides from Glycosmis pentaphylla. J Asian Nat Prod Res. 2014 Dec;16(12):1119-25. [Content Brief]
