Phenolic glycosides from Glycosmis pentaphylla

  • J Asian Nat Prod Res. 2014 Dec;16(12):1119-25. doi: 10.1080/10286020.2014.951924.
Er-Li Tian  1 Yuan-Yuan Cui Guang-Zhong Yang Zhi-Nan Mei Yu Chen
Affiliations
  • 1. a College of Chemistry and Materials Science, South Central University for Nationalities , Wuhan 430074 , China.
Abstract

Three new phenolic glycosides, named as glycopentosides A-C (1-3), along with nine known compounds were isolated from the n-BuOH extract of stems of Glycosmis pentaphylla. Their structures were determined by using spectroscopic and chemical methods. Bioassay showed that compound 10 (tachioside) could inhibit nitric oxide production in lipopolysaccharides-stimulated RAW 264.7 cells with IC50 value of 12.14 μM.

Keywords
Glycosmis pentaphylla; Rutaceae; nitric oxide production; phenolic glycosides.
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