1092502-33-4
Chemical Structure
GW 833972A
- CAS No.: 1092502-33-4
- Formula:C18H14Cl2F3N5O
- Molecular Weight:444.24
IUPAC Name: 2-((3-chlorophenyl)amino)-N-(pyridin-4-ylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide hydrochloride
InChIKey: UBHSVFAUAKIVKL-UHFFFAOYSA-N
SMILES: O=C(C1=CN=C(NC2=CC=CC(Cl)=C2)N=C1C(F)(F)F)NCC3=CC=NC=C3.[H]Cl
Biological Activity: GW 833972A is a selective CB₂ receptor agonist with pEC₅₀ of the human CB₂ receptor for GW 833972A of 7.3, and its selectivity for the CB₂ receptor is approximately 1000 times higher than that for the CB₁ receptor. GW 833972A inhibits induced neuronal depolarization and suppresses coughing caused by citric acid in guinea pig models. GW 833972A can be used for the study of chronic cough[1].
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GW 833972A | 99.91% | GW 833972A is a selective CB₂ receptor agonist with pEC₅₀ of the human CB₂ receptor for GW 833972A of 7.3, and its selectivity for the CB₂ receptor is approximately 1000 times higher than that for the CB₁ receptor. GW 833972A inhibits induced neuronal depolarization and suppresses coughing caused by citric acid in guinea pig models. GW 833972A can be used for the study of chronic cough. | ||||||||||||||||||||
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GW 833972A (Standard) | ≥98% | GW 833972A (Standard) is the analytical standard of GW 833972A (HY-101765). This product is intended for research and analytical applications. GW 833972A is a selective CB₂ receptor agonist with pEC₅₀ of the human CB₂ receptor for GW 833972A of 7.3, and its selectivity for the CB₂ receptor is approximately 1000 times higher than that for the CB₁ receptor. GW 833972A inhibits induced neuronal depolarization and suppresses coughing caused by citric acid in guinea pig models. GW 833972A can be used for the study of chronic cough. | ||||||||||||||||||||
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Keywords
