1092788-97-0
1092788-97-0
Chemical Structure
PP162
- CAS No.: 1092788-97-0
- Formula:C17H17N7
- Molecular Weight:319.36
IUPAC Name: 1-cyclopentyl-3-(imidazo[1,2-a]pyridin-7-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
InChIKey: DTUMIKLOEHJGJT-UHFFFAOYSA-N
SMILES: NC1=C2C(N(C3CCCC3)N=C2C4=CC5=NC=CN5C=C4)=NC=N1
Biological Activity: PP162 is a selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 53 nM. PP162 selectively inhibits DNA-PK by binding to a conserved hydrophobic pocket. PP162 exhibits weak inhibitory activity against various tyrosine kinases and PI3K family members. PP162 can be used for research on selective kinase targeting[1].
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PP162 | PP162 is a selective DNA-dependent protein kinase (DNA-PK) inhibitor with an IC50 of 53 nM. PP162 selectively inhibits DNA-PK by binding to a conserved hydrophobic pocket. PP162 exhibits weak inhibitory activity against various tyrosine kinases and PI3K family members. PP162 can be used for research on selective kinase targeting. | |||||||||||||||||||||
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