109636-76-2
109636-76-2
Chemical Structure
Prinomide tromethamine
- CAS No.: 109636-76-2
- Formula:C19H24N4O5
- Molecular Weight:388.42
IUPAC Name: 2-cyano-3-(1-methyl-1H-pyrrol-2-yl)-3-oxo-N-phenylpropanamide compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
InChIKey: CPUJDORGQAJDCT-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=CC=C1)C(C(C2=CC=CN2C)=O)C#N.OCC(N)(CO)CO
Biological Activity: Prinomide tromethamine is an orally available nonsteroidal anti-inflammatory agent. Prinomide tromethamine can be used to study inflammation, such as rheumatoid arthritis[1][2].
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Prinomide tromethamine | Prinomide tromethamine is an orally available nonsteroidal anti-inflammatory agent. Prinomide tromethamine can be used to study inflammation, such as rheumatoid arthritis. | |||||||||||||||||||||
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References
- [1]. Egger H, et al. Disposition and metabolism of prinomide in laboratory animals. Drug Metab Dispos. 1988 Jul-Aug;16(4):568-75. [Content Brief]
- [2]. Doughty JR, et al. Relationship of blood markers to disease severity and drug efficacy in rat adjuvant arthritis. Agents Actions. 1991 Sep;34(1-2):129-31. [Content Brief]
