109666-14-0
Chemical Structure
5-(Aminomethyl)-2-thiouridine
- CAS No.: 109666-14-0
- Formula:C10H15N3O5S
- Molecular Weight:289.31
IUPAC Name: 5-(aminomethyl)-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
InChIKey: LOEDKMLIGFMQKR-JXOAFFINSA-N
SMILES: O=C(C(CN)=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)NC1=S
Biological Activity: 5-(Aminomethyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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5-(Aminomethyl)-2-thiouridine | 5-(Aminomethyl)-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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Keywords