110714-10-8
Chemical Structure
GYKI 12743
- CAS No.: 110714-10-8
- Formula:C16H20ClN3O3
- Molecular Weight:337.80
IUPAC Name: 2-(3-(((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)amino)propyl)pyridazin-3(2H)-one hydrochloride
InChIKey: WJDFSAOMSJHHCG-UHFFFAOYSA-N
SMILES: O=C(C=CC=N1)N1CCCNCC2OC3=C(C=CC=C3)OC2.Cl
Biological Activity: GYKI 12743 is a vasoselective, postsynaptic α-adrenoceptor blocker. GYKI 12743 inhibits but does not completely eliminate the cutaneous microcirculatory blood flow reduction evoked by electrical stimulation of the peripheral stump of the cut saphenous nerve in rats. GYKI 12743 can be used for the study of neurological diseases[1].
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GYKI 12743 | GYKI 12743 is a vasoselective, postsynaptic α-adrenoceptor blocker. GYKI 12743 inhibits but does not completely eliminate the cutaneous microcirculatory blood flow reduction evoked by electrical stimulation of the peripheral stump of the cut saphenous nerve in rats. GYKI 12743 can be used for the study of neurological diseases. | |||||||||||||||||||||
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Keywords