111200-01-2
Chemical Structure
7-Ethoxyrosmanol
- CAS No.: 111200-01-2
- Formula:C22H30O5
- Molecular Weight:374.47
IUPAC Name: (4bR,8aS,9S,10S)-10-ethoxy-3,4-dihydroxy-2-isopropyl-8,8-dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epoxymethano)phenanthren-12-one
InChIKey: HEUIVINVBVPWCU-WEMPKCCASA-N
SMILES: O=C1O[C@]2([H])[C@@H](OCC)C3=C(C(O)=C(O)C(C(C)C)=C3)[C@@]41CCCC(C)(C)[C@]24[H]
Biological Activity: 7-Ethoxyrosmanol is a phenolic diterpene that is isolated from Salvia chamelaeagnea. 7-Ethoxyrosmanol has antioxidant activity in vitro and antitumor effects on neuroblastoma cells. 7-Ethoxyrosmanol alleviates hyperglycemia-induced endothelial cell dysfunction via regulating FBXL7[1][2][3].
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7-Ethoxyrosmanol | 7-Ethoxyrosmanol is a phenolic diterpene that is isolated from Salvia chamelaeagnea. 7-Ethoxyrosmanol has antioxidant activity in vitro and antitumor effects on neuroblastoma cells. 7-Ethoxyrosmanol alleviates hyperglycemia-induced endothelial cell dysfunction via regulating FBXL7. | |||||||||||||||||||||
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- [1]. Ni J, et al. 7-Ethoxyrosmanol alleviates hyperglycemia-induced vascular endothelial dysfunction by regulating FBXL7 expression. J Bioenerg Biomembr. 2021 Oct;53(5):553-560. [Content Brief]
- [2]. Tabata K, et, al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov; 32(11): 4781-9. [Content Brief]
- [3]. Etsassala NGER, et, al. Investigation of In-Vitro Antioxidant and Electrochemical Activities of Isolated Compounds from Salvia chamelaeagnea P.J.Bergius Extract. Antioxidants (Basel). 2019 Apr 12; 8(4): 98. [Content Brief]
Keywords
